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Treatments targeting some of the abnormalities seen in ASD including neurotransmitter abnormalities, particularly imbalances in glutamate and acetylcholine, sleep onset disorder (with behavioral therapy and melatonin), and metabolic abnormalities in folate, cobalamin, tetrahydrobiopterin, carnitine, and redox pathways are being investigated

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Santana-Glvez, J., Cisneros-Zevallos, L., & Jacobo-Velzquez, D

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Non-pharmacological approaches involve addressing the underlying causes of cirrhosis and adhering to the validated TrACE (Treating causes, Ameliorating modifiable factors, Coping mechanisms, and Empathizing) model, particularly used to manage fatigue in primary biliary cholangitis